Edwards fronted the AFL's concussion panel last week in Melbourne after suffering three concussions already this year.
The 25-year-old has now been ruled out for the rest of the season, but importantly, he has been given hope he can resume his 57-game career next year.
Edwards will undergo a three-month concussion program before being reassessed.
"It's a positive result," McQualter said.
"We know that he's just got to go through a three-month rehabilitation process now and work through those protocols.
"But Harry's a much-loved member of our team and our club and important to us, so he'll go away and do that, and then we're hopeful that he's still got a long career ahead of him."
The absence of Edwards and fellow key back Reuben Ginbey (quad) has left West Coast exposed against some of the AFL's best key forwards.
It means Tylar Young and Rhett Bazzo will again have their hands full when West Coast host Adelaide at Optus Stadium on Friday night, with Eagles forward Jack Williams earning a recall to play as a key defender.
The trio will be relied upon to restrict Adelaide's tall forward line of Darcy Fogarty, Taylor Walker and Riley Thilthorpe.
West Coast will also be bolstered by the return of star on-baller Tim Kelly (hamstring), while mid-season recruit Oliver Francou will make his AFL debut to add more midfield grunt.
The Eagles (4-11) were blitzed in the midfield in last week's 53-point loss to Carlton.
Francou, the son of former Port Adelaide midfielder Josh Francou, has starred in the WAFL since being picked up by West Coast, averaging 24 disposals and eight tackles per game across his four matches.
"He's made a huge impact at this footy club in a short period of time," McQualter said.
"He missed most of last year through injury, so he snuck under everyone's radar and missed out on the draft.
"But even his first five or six games in the SANFL this year (before being recruited by the Eagles) were so strong and powerful. He's a contested ball player ... but he's also got more run in his game than people realise."
Adelaide (9-6) are desperate to bounce back after suffering a shock 26-point loss to arch rivals Port Adelaide last week.
"They're really hard-working, blue-collar," McQualter said of the Crows.
"Their last six or seven weeks has been really strong.
"They probably had a disappointing day ... they would say last week. Port got a hold of them, but they're a good team."
Star Crows midfielder Izak Rankine will face the Eagles despite tweaking his ankle and knee last week.
