More than 300 Gazans have been killed in Israeli strikes since Thursday, according to local health authorities, one of the deadliest phases of bombardment since a truce collapsed in March.Â
The latest strikes came after US President Donald Trump ended his Middle East tour on Friday with no apparent progress towards a new ceasefire.
"Since midnight, we have received 58 martyrs, while a large number of victims remain under the rubble. The situation inside the hospital is catastrophic," said the director of the Indonesian Hospital in northern Gaza, Marwan Al-Sultan.
Israel's military said on Saturday it is conducting extensive strikes and mobilising troops as part of preparations to expand operations in the Gaza Strip and achieve "operational control" in areas of the Palestinian enclave.
The escalation, which includes the build-up of armoured forces along the border, is part of the initial stages of Operation Gideon's Wagons, which Israel says is aimed at defeating Hamas and getting its hostages back.
An Israeli defence official said earlier this month the operation would not be launched before Trump concluded his visit to the Middle East.
United Nations experts warn that famine looms in Gaza after Israel blocked aid deliveries to the strip 76 days ago, with UN aid chief Tom Fletcher asking the Security Council this week if it would act to "prevent genocide".
Trump on Friday acknowledged Gaza's growing hunger crisis and the need for aid deliveries, as international pressure grows on Israel to resume ceasefire talks and end its blockade of Gaza.
Prime Minister Benjamin Netanyahu said on May 5 that Israel was planning an expanded, intensive offensive against Hamas as his security cabinet approved plans that could involve seizing the entire Gaza Strip and controlling aid.
Separately, Israel struck Yemen's Red Sea ports of Hodeidah and Salif, continuing its campaign to degrade Houthi military capabilities.
The Houthis have continued to fire missiles at Israel in what they say is solidarity with Palestinians in the Gaza Strip, although they have agreed to halt attacks on US ships.
Israel has carried out retaliatory strikes in response, including one on May 6 that damaged Yemen's main airport in Sanaa and killed several people.
On Friday, the Israeli military said it dropped more than 30 munitions on Houthi targets in its eighth such attack. It said the ports of Hodeidah and Salif were being used to transfer weapons, reiterating its warnings to residents of those areas to evacuate.
The Israeli strikes killed at least one person and injured nine, the Houthi-run health ministry said in a statement.
Netanyahu and Defence Minister Israel Katz said in a joint statement they would hunt down the Houthis' top leader, Abdul Malik al-Houthi.
"If the Houthis continue to fire missiles at the State of Israel, they will be severely harmed, and we will also hurt the leaders," they said, adding that al-Houthi could join the list of militant figures killed by Israel, such as Hamas' Yahya Sinwar and Hezbollah's Hassan Nasrallah.
Mohammed Ali al-Houthi, a senior group figure, described the Israeli threats as "illusions", saying on X that they were aimed at buying time by setting "unattainable goals."
The Houthis are part of Iran's so-called "Axis of Resistance" against Israeli and US interests in the Middle East, alongside Hamas in Gaza and Hezbollah in Lebanon.
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