Almost 1000 DNA statements spanning the past three years are being reviewed by Forensic Science Queensland after a scientist spotted a typographical error while giving evidence in court.
It triggered a wider review, with about 10 to 15 per cent of the first 300 statements checked containing mistakes such as incorrect case numbers or dates.
Forensic Science Queensland insisted the underlying DNA analysis remained sound.
"The thing that's important ... is that the science is right," director Mick Fuller said.
"It is merely the information that has been taken from the science into the statement."
The state lab has written to police and the Director of Public Prosecutions with exact case numbers and corrected statements for every error located to date.
Mr Fuller said he could not categorically rule out a case would ultimately be affected as the audit continued.
"It'd be impossible for me to say no, of course," he said when asked if a prosecution could still be compromised.
The review covered any DNA matter for which the state lab issued a statement over the past three years, including rapes and murders.
Attorney-General Deb Frecklington said there was no evidence to date that any convictions or victims had been harmed by the flaws.
She characterised the problem as transcription slip-ups in names or numbers rather than faulty testing.
"It did not affect the criminal outcome of the matter, and it hasn't, and we've been very forthright with that."
The attorney-general argued the discovery showed improved transparency and governance at a lab already rocked by a previous debacle which first blew up in late 2021, when serious flaws in DNA profiling were exposed.
A subsequent review and commission of inquiry found testing errors had wrongly deemed samples too weak to analyse, forcing about 30,000 cases to be revisited.
Mr Fuller said he inherited "poor governance and poor transparency" at the state lab and was still trying to lift quality assurance across the board.
"I can only apologise that mistakes were made, but all I can do is ensure that we have the best governance systems in place, and that we are being absolutely transparent."
The lab has strengthened its peer review system, added independent checks, and is seeking to automate the flow of key details from forensic registers into statements to reduce manual transcription.
The controversy has erupted as the state government trumpets new technology and fresh funding as evidence it is repairing Queensland's forensic system after what it calls one of the worst DNA failures in a justice system.
Two new robotic DNA processors are now operating at FSQ, replacing ageing equipment that failed under the previous Labor government and was blamed for contamination events and backlogs affecting about 13,000 cases.
The government says the major crime DNA backlog has been cut by more than 80 per cent, from 11,703 untested samples in November 2024 to 2240 in July 2026.